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Acknowledging ZBP1 expands our understanding of how aberrant mtDNA contributes to innate immune signaling in NDDs and highlights additional potential targets for therapeutic modulation of sterile inflammation [104]

LTA 4 H, leukotriene A 4 hydrolase

A notable characteristic of this intein is its ability to splice efficiently in the presence of very diverse flanking extein sequences, while the split intein segments were also much more soluble during expression due to this being their native state

It has also been reported that human GST class Omega, GSTO1-1, modulates calcium channel (ryanodine receptors, RyRs) protecting mammalian cells from apoptosis induced by calcium (Ca 2+ ) mobilization [57]